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专利名称：Fluoresence assay for mtp activity发明人：M. Mahmood Hussain,Humra Athar,Jahangir
Igbal
申请号：US10535863申请日：20040625
公开号：US200602287A1公开日：20061012
摘要：The present invention is directed to methods for assaying microsomaltriglyceride transfer protein (MTP) which are amenable to automation and high-throughput screening. The assays may be used to measure MTP activity in cell and tissuehomogenates as well as purified MTP. The methods provided by the present inventionhave the advantages of ease, rapidity, sensitivity, avoidance of the use of negativelycharged lipids, versatility in studying different lipid transfer activities by purified andcellular MTP and the ability to measure inhibitory activity. In addition, methods ofidentifying compounds that modulate the lipid transfer activity of MTP are provided. Kitsfor measuring the lipid transfer activity of MTP are provided by the present invention
申请人：M. Mahmood Hussain,Humra Athar,Jahangir Igbal
地址：Woodbury NY US,Brookline MA US,Jersey City NJ US
国籍：US,US,US
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