专利内容由知识产权出版社提供
专利名称：POLYCONJUGATES FOR IN VIVO DELIVERY
OF POLYNUCLEOTIDES
发明人：ROZEMA, DAVID B.,WAKEFIELD, DARREN
H.,WOLFF, JON A.,WONG, SO,KLEIN,JASON,LEWIS, DAVID L.,HAGSTROM, JAMESE.,BLOKHIN, ANDREI,TRUBETSKOY,VLADIMIR,HERWEIJER, HANS
申请号：EP07841047申请日：20070817公开号：EP2061443A4公开日：20130724
摘要：The present invention is directed to a class of membrane active polymers usefulfor cellular delivery of compounds. Conjugation of the described membrane activepolymers to targeting, anti-opsonization, and anti-aggregation agents provides polymerssuitable for in vivo delivery. The use of multiple reversible linkages connectingcomponent parts provides for physiologically responsive activity modulation.
申请人：ARROWHEAD RESEARCH CORPORATION
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