专利内容由知识产权出版社提供
专利名称：Intrathymic stem cell implantation发明人：MARGARET D ALLEN,ROBERT G ANDREWS申请号：AU4236296申请日：19951109公开号：AU4236296A公开日：19960606
摘要：Engraftment of grafts in transplant recipients are enhanced by implantingCD34-positive hematopoietic cells obtained from the graft donor in the thymus of thetransplant recipient. The methods enhance engraftment of both allogeneic andxenogeneic transplants. Methods are also provided for supplying a gene product ofinterest in a host mammal by implanting in the thymus of the host CD34-positivehematopoietic progenitor cells which encode the gene product of interest. The CD34-positive hematopoietic cells can be genetically engineered to produce the gene productof interest in the recipient host.
申请人：UNIVERSITY OF WASHINGTON,FRED HUTCHINSON CANCER RESEARCHCENTER
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