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Phenylserine derivatives and processes for prepari

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专利名称:Phenylserine derivatives and processes for

preparing the same

发明人:Naohito Ohashi,Shoji Nagata,Masashi

Nakatsuka,Kikuo Ishizumi,JunkiKatsube,Shunji Aono,Teruo Sakurama

申请号:US06/683430申请日:19841219公开号:US04695580A公开日:19870922

摘要:Novel phenylserine derivatives of the formula: ##STR1## and pharmaceuticallyacceptable acid addition salts thereof, pharmaceutical compositions, and a process forpreparing the compounds are disclosed. The phenylserine derivatives and

pharmaceutically acceptable acid addition salts are capable of inhibiting the biosynthesisof leucotrienes and/or antagonistic activity against SRS-A and hence are useful forprophylaxis and treatment of various allergic diseases (e.g. bronchial asthma, allergicnasitis, urticaria), ischemic heart diseases, ischemic encephalopathy, inflammation, or thelike.

申请人:SUMITOMO PHARMACEUTICALS COMPANY, LTD.

代理机构:Birch, Stewart, Kolasch & Birch

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